N-Methylindole-6-carboxylic acid methyl ester is an organic compound with molecular formula C11H11NO2 and molecular weight of 189.21g/mol. It is a light yellow to light brown solid with a special aroma.
N-Methylindole-6-carboxylic acid methyl ester is mainly used as a raw material in the preparation of drugs and organic synthesis reactions. It can be used as an intermediate for the synthesis of various biologically active indole compounds, such as the synthesis of indole carboxylic acid derivatives, indole formamide, etc. In addition, it can also be used for synthetic dyes, fragrances and high-performance polymers.
N-Methylindole-6-carboxylic acid methyl ester is usually prepared by the reaction of indole and methyl formate. The specific preparation method can be as follows: adding excess methyl formate in a suitable solvent, then slowly adding indole dropwise, heating during the reaction, and crystallization purification after the reaction.
Regarding safety information, N-Methylindole-6-carboxylic acid methyl ester is generally relatively safe under ordinary operating conditions, it is still necessary to follow general laboratory safety practices, such as wearing appropriate personal protective equipment (such as gloves, goggles, and lab clothes), and avoiding inhalation, skin contact, and ingestion. In addition, adequate risk assessment and safety measures are required for the use and handling of any chemical. When using should follow the relevant regulations and guidelines.